Thanks to the generosity of our corporate and individual donors, our foundation is helping pediatric and adult sarcoma patients in the Carolinas gain access to cutting-edge treatments by providing SARC038 trial site funding at Levine Cancer Institute and Levine Children’s Hospital. In funding these sites, we are bringing novel therapies to patients where they live so that families are relieved of the stress of long-distance travel to find new treatments.
This clinical trial will open shortly and can enroll patients as young as 5 years old. The clinical trial drugs are a targeted therapy and an immunotherapy. Every effort will be made to ensure that 50% of patients will be ≤ 21 years of age.
TYPE OF SARCOMA: Osteosarcoma
DRUG: Regorafenib, Nivolumab
ACCRUAL STATUS: Recruiting
OVERALL STUDY PRINCIPAL INVESTIGATORS:
Fariba Navid, MD
Children’s Hospital of Los Angeles
Lara Davis, MD
Oregon Health and Sciences University
CLINICALTRIALS.GOV IDENTIFIER: NCT04803877
FOR STUDY DETAILS AND ELIGIBILITY CRITERIA: CLINICALTRIALS.GOV
Dr. Fariba Navid, Principal Investigator of SARC038, speaks about the clinical trial.
Read all of the clinical trial details on the ClinicalTrials.gov website.
SARC038 on ClinicalTrials.gov
Learn About Levine Cancer Institute and Levine Children's Hospital in Charlotte, NC, two nationally-ranked cancer centers that have expertise in osteosarcoma cancers.
Learn about these cancer centersOsteosarcoma is the most common type of bone cancer. Osteosarcoma usually starts in osteoblasts, which are a type of bone cell that becomes new bone. Osteosarcoma is most common in adolescents. It commonly forms in the ends of the long bones of the body, which include bones of the arms and legs. In children and adolescents, it often forms in the long bones, near the knee. Rarely, osteosarcoma may be found in soft tissue or organs in the chest or abdomen.
These and other signs and symptoms may be caused by osteosarcoma or by other conditions. Check with a doctor if your child has any of the following:
Source (and to learn more): National Cancer Institute
What is Sarcoma? Sarcoma is a cancer of the bone or connective tissue, such as nerves, muscles, cartilage, tendons, fat, and blood vessels that can occur in the arms, legs, chest, abdomen, head or neck. There are over 150 subtypes of sarcomas. Sarcomas comprise less than 1% of adult cancers and approximately 15% of pediatric cancers. Around 16,000 individuals are diagnosed with bone or soft-tissue sarcoma in the U.S. each year.
Taking action quickly is critical to a positive outcome, so head to our RESOURCES section to access information about sarcoma education, sarcoma treatments, and family support via links to high-quality organizations and sources.
Download our Sarcoma poster Download our Sarcoma poster
